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When a compound can induce dramatic physiological changes, like the significant weight loss often seen in tirzepatide studies, it's bound to have downstream effects

35 GLP1-GIP combination has been reported to reduce GLP-1-caused gastrointestinal problems, 36 therefore, the combination of GLP1-GIP-FGF21 may have a significant effect on both glucose and lipid metabolism while minimizing gastrointestinal discomfort

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This pathway promotes thermogenesisyour bodys process of burning calories for heatand encourages the breakdown of stored fat for energy